guanosine 5'-monophosphate — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD	Monosodium-GMP,cGMP sodium salt,Cyclic GMP	PKA
	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, inc...		PKA
T4901	5'-Guanylic acid disodium salt	Guanosine 5'-monophosphate disodium salt,GMP-5	Others , Endogenous Metabolite
	5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthy...		Others , Endogenous Metabolite
T19346	5'-Guanylic acid	5'-guanosine monophosphate,5'-GMP	Endogenous Metabolite
	5'-Guanylic acid (5'-guanosine monophosphate) is involved in several metabolic disorders, including AICA-ribosiduria pathway, adenosine deaminase deficiency,adenine phosphoribosyltransferase deficiency (aprt), and the 2-...		Endogenous Metabolite
T0467	Sildenafil citrate	UK-92480 citrate	Apoptosis , PDE , Autophagy
	Sildenafil citrate (UK-92480 citrate) , a cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) Inhibitor, is used extensively for erectile dysfunction and less commonly for pulmonary hypertensio...		Apoptosis , PDE , Autophagy
T37636	2'-Deoxyguanosine 5'-monophosphate disodium	5′-dGMP disodium	Endogenous Metabolite
	2'-Deoxyguanosine 5'-monophosphate disodium (5'-dGMP disodium) is a nucleic acid guanosine triphosphate (GTP) derivative that serves as an oxidizable target and can be used in the formation of polycomplexes with other co...		Endogenous Metabolite
T77570	AP-C2		PKA
	AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.		PKA
T23411L	T-0156	T 0156	PDE , Parasite
	T-0156 is a novel, potent and selective phosphodiesterase type 5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinity for PDE6, PDE1, PDE2, PDE3 and PDE4.		PDE , Parasite
T1398	Tadalafil	Cialis,IC-351	Apoptosis , PDE
	Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGM...		Apoptosis , PDE
T60500	AP-C5		Parasite
	AP-C5 is a compound with selective inhibition of guanosine 3',5' cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), with a Pic50 value of 7.2 for cGMP, and can be used in the study of diarrheal diseases.		Parasite
T0096	Vardenafil	Vivanza,Levitra,Vardenafil hydrochloride	PDE
	Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemod...		PDE
T69593	Sildenafil nitrate
	Sildenafil nitrate is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP).
T11400	Gisadenafil besylate	UK 369003-26	Others
	Gisadenafil besylate (UK 369003-26) is a specific, orally active phosphodiesterase 5 (PDE5) inhibitor ,prevents degradation of cyclic guanosine monophosphate (cGMP), with an IC50 of 3.6 nM .		Others
T82990	AP-C4
	AP-C4 is a selective inhibitor targeting guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 5.2. Conversely, AP-C3 does not inhibit cGKII-mediated anion secretion...
T82991	AP-C3
	AP-C3 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 6.3 and demonstrating only weak inhibition of cGKII-dependent anion secretion [1...
T63246	BMS-566419
	BMS-566419 is an acridinone-based inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH), a key enzyme for the de novo synthesis of guanosine nucleotides. BMS-566419 has clinical utility in the study of graft reject...
T82989	AP-C6
	AP-C6 is a potent inhibitor of guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 of 6.5. It inhibits human cGKII activity in vitro in a concentration-dependent manner and...
T63776	PDE1-IN-4
	PDE1-IN-4 is a potent and selective inhibitor of PDE1 (phosphodiesterase-1), acting on PDE1C (IC50: 10 nM), PDE1A (IC50: 145 nM) and PDE1B (IC50: 354 nM). PDE1-IN-4 regulates cAMP (3′,5′-cyclic adenosine monophosphate) a...